Computer Aided Drug Design - CADD
Development of Thyroid Receptor Alpha Agonist to Stimulate Cardiac Regeneration Using Computational Biology Techniques and in Vitro Assays
Cardiovascular diseases are among the most deadly worldwide, wherein ischemic diseases are the most lethal. Considering the regenerative potetial stimulated by the thyroid hormone over the heart, we use computational biology techniques to select and optimize agonist molecules of the thyroid receptor alpha, through molecular dynamics, aiming to develop potential drugs for the treatment of cardiac injuries.
