TARDIS: A genome-scale metabolic network tool to identify new targets for computer-aided antimicrobial design
Throughout history, many alternatives for tackling epidemics have been adopted, and yet we still observe outbreaks of infectious diseases taking on devastating proportions. With the advancement of bioinformatics, computer-aided drug design (CADD) methodologies have emerged to reduce the time and cost required for the development of new drugs. However, this field suffers from a scarcity of new targets for pharmacological intervention, making it necessary to develop new methodologies to meet this demand. Therefore, this project aims to develop TARDIS: TARgets DIScoverer, a program for identifying molecular targets in bacterial genomes in an automated and user-friendly way.
Team: Camila Rodrigues Chaves, Artur Duque Rossi, Guilherme Ian Spelta, Pedro Torres